All explainers
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Body Image After Ostomy Surgery for Cancer: What a 2026 Systematic Review Found
Body image concerns are one of the most consistent findings in research on life after ostomy surgery for cancer. A systematic review published in July 2026 maps the patterns: what most people report, what makes adjustment harder, and what the evidence says actually helps.

Vaccines and IBD: What the Guidelines Say About Timing Around Biologics and Immunosuppression
For people with inflammatory bowel disease on immunosuppressive treatment, vaccination is a planned, timing-sensitive part of care. International guidelines agree on a few clear principles: sort out vaccines early, give live vaccines before treatment where possible, and rely on inactivated vaccines once treatment has started.

Can IBD Affect Memory and Thinking? A 2026 Systematic Review of 66 Studies Investigates
A systematic review published in the Journal of Crohn's & Colitis in May 2026 searched PubMed and Scopus through August 2024, analysing 66 studies from population research, genetic investigations, and preclinical models, and found that patients with IBD may exhibit impaired cognitive function, particularly in memory, attention, and executive processing, with disease activity, chronic inflammation, and psychological stress among the contributing factors identified.

Stigma After Stoma Surgery: What a 2026 Evidence Review Found About Screening and Support
A 2026 literature review in Frontiers in Oncology identified approaches to detecting felt stigma in colorectal cancer patients with stomas and summarised evidence on which interventions provide meaningful support.

The Gut-Brain Axis in IBD: What a 2026 Systematic Review of 1,040 Patients Found About Microbiota and Mood
A systematic review published in Frontiers in Microbiology in June 2026 analysed ten studies involving 1,040 IBD patients and found that anxiety and depressive symptoms were associated with reduced gut microbial diversity and enrichment of pro-inflammatory bacterial taxa, with authors concluding the relationship may be bidirectional.

Beyond the Bowel: What a 2025 Cochrane Review Found About Psychological Interventions in IBD
A 2025 Cochrane systematic review and meta-analysis by Tiles-Sar and colleagues examined the randomised trial evidence for psychological interventions in inflammatory bowel disease, assessing whether approaches such as cognitive behavioural therapy, mindfulness, and stress management affect disease activity, quality of life, and psychological wellbeing.

Learning to Live With IBD: What a Cochrane Review Found About Patient Education Programs
A 2023 Cochrane systematic review examined the trial evidence for structured patient education interventions in inflammatory bowel disease, assessing whether programmes delivered by nurses, clinicians, or digital tools affect disease activity, quality of life, and patients' ability to manage their own condition.

Telehealth for IBD: What a Cochrane Review Found About Remote Care
A Cochrane systematic review evaluated whether digital and remote care tools, including apps, telephone follow-up, and web-based monitoring platforms, change outcomes for people living with inflammatory bowel disease. Here is what the evidence found, and why certainty still matters.

After Crohn's Surgery: The Growing Case for Intestinal Ultrasound as a Monitoring Tool
A 2026 international consensus study published in The Lancet Gastroenterology & Hepatology used the RAND/UCLA appropriateness method to evaluate exactly when intestinal ultrasound is appropriate for detecting postoperative Crohn's disease recurrence, drawing on 21 international experts to produce the first structured guidance on this non-invasive monitoring approach.

Azathioprine and 6-MP for Ulcerative Colitis: A 2025 Cochrane Review on Long-Term Remission
A 2025 Cochrane systematic review synthesises randomised trial evidence on azathioprine and 6-mercaptopurine for maintaining remission in ulcerative colitis. These widely used medications have decades of clinical history, but patients often have questions about what the evidence actually shows and what routine monitoring involves.

When One IBD Treatment Is Not Enough: A 2026 Review on Combining Biologics
A systematic review and meta-analysis pooling 52 studies and 2,022 participants found early safety signals for combining two advanced IBD drugs, but the certainty of evidence is rated very low across all analyses.

Vitamin D and IBD: What a Cochrane Review of 22 Trials Found — and What Remains Uncertain
A 2023 Cochrane systematic review examined 22 randomised controlled trials with 1,874 participants living with IBD. The review found a possible reduction in clinical relapse with vitamin D supplementation — but rates certainty of evidence as low, and cannot yet draw conclusions on quality of life or disease response.