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Sourced explainer· Research, plainly· Reviewed 15 May 2026

Beyond bacteria: why researchers are now looking at gut viruses and fungi in IBD

A 2026 review argues the gut's viruses and fungi have been comparatively overlooked in inflammatory bowel disease. Here's what that does — and does not — mean for patients.

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A quiet, sunlit room with an empty armchair and a small plant — calm, unhurried, no people.

When people talk about the "gut microbiome," they usually mean bacteria. For inflammatory bowel disease — ulcerative colitis and Crohn's disease, where parts of the gut become inflamed [1] — bacteria have been the main focus of research for years.

A 2026 review makes a simple point: bacteria are not the only residents of the gut. Viruses (together called the virome) and fungi (the mycobiome) live there too, and the review argues they have been comparatively neglected — while possibly playing a role in IBD as well [2].

It's worth being precise about what this is. This is a review — a summary of existing evidence and open questions — not a single new experiment, and not a result that changes how IBD is diagnosed or treated [3]. It points at a direction researchers think is worth more attention, which is different from saying anything is settled.

For someone living with IBD, the practical takeaway is small and honest: the science of the gut is still expanding, and "microbiome" is broader than bacteria alone. It is not a reason to change anything you are doing. If you are weighing what any of this means for your own situation, your clinician knows your case best — ask them first.

Sources

  1. NHS — Inflammatory bowel disease (T1, authority guidance): https://www.nhs.uk/conditions/inflammatory-bowel-disease/
  2. "Neglected kingdoms: the gut virome, mycobiome and their role in inflammatory bowel disease" — Gut Microbes, 2026 (T2, review): https://doi.org/10.1080/19490976.2026.2653288
  3. Same review as [2] — characterised as a review of evidence and open questions.

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